Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature

A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range polymerase chain reaction (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lane-Donovan, Courtney, Bainbridge, Emma, Szumowski, John, Kerkhoff, Andrew D, Peluso, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Novel ID Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088507/
https://www.ncbi.nlm.nih.gov/pubmed/35559128
http://dx.doi.org/10.1093/ofid/ofab450
_version_ 1784704347992489984
author Lane-Donovan, Courtney
Bainbridge, Emma
Szumowski, John
Kerkhoff, Andrew D
Peluso, Michael J
author_facet Lane-Donovan, Courtney
Bainbridge, Emma
Szumowski, John
Kerkhoff, Andrew D
Peluso, Michael J
author_sort Lane-Donovan, Courtney
collection PubMed
description A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range polymerase chain reaction (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially treated infections.
format Online
Article
Text
id pubmed-9088507
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-90885072022-05-11 Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature Lane-Donovan, Courtney Bainbridge, Emma Szumowski, John Kerkhoff, Andrew D Peluso, Michael J Open Forum Infect Dis Novel ID Cases A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range polymerase chain reaction (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially treated infections. Oxford University Press 2021-10-30 /pmc/articles/PMC9088507/ /pubmed/35559128 http://dx.doi.org/10.1093/ofid/ofab450 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Novel ID Cases
Lane-Donovan, Courtney
Bainbridge, Emma
Szumowski, John
Kerkhoff, Andrew D
Peluso, Michael J
Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature
title Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature
title_full Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature
title_fullStr Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature
title_full_unstemmed Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature
title_short Mycobacterium avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient With AIDS: Case Report and Review of the Literature
title_sort mycobacterium avium complex infection as a rare cause of cerebral mass lesion and iris in a patient with aids: case report and review of the literature
topic Novel ID Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088507/
https://www.ncbi.nlm.nih.gov/pubmed/35559128
http://dx.doi.org/10.1093/ofid/ofab450
work_keys_str_mv AT lanedonovancourtney mycobacteriumaviumcomplexinfectionasararecauseofcerebralmasslesionandirisinapatientwithaidscasereportandreviewoftheliterature
AT bainbridgeemma mycobacteriumaviumcomplexinfectionasararecauseofcerebralmasslesionandirisinapatientwithaidscasereportandreviewoftheliterature
AT szumowskijohn mycobacteriumaviumcomplexinfectionasararecauseofcerebralmasslesionandirisinapatientwithaidscasereportandreviewoftheliterature
AT kerkhoffandrewd mycobacteriumaviumcomplexinfectionasararecauseofcerebralmasslesionandirisinapatientwithaidscasereportandreviewoftheliterature
AT pelusomichaelj mycobacteriumaviumcomplexinfectionasararecauseofcerebralmasslesionandirisinapatientwithaidscasereportandreviewoftheliterature

Ejemplares similares