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Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis

Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at the glia limitans, where it mediates water exchange across the blood–spinal cord and blood–brain barriers (BSC...

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Detalles Bibliográficos
Autores principales: Salman, Mootaz M, Kitchen, Philip, Halsey, Andrea, Wang, Marie Xun, Törnroth-Horsefield, Susanna, Conner, Alex C, Badaut, Jerome, Iliff, Jeffrey J, Bill, Roslyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088512/
https://www.ncbi.nlm.nih.gov/pubmed/34499128
http://dx.doi.org/10.1093/brain/awab311