Cargando…

Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis

Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at the glia limitans, where it mediates water exchange across the blood–spinal cord and blood–brain barriers (BSC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salman, Mootaz M, Kitchen, Philip, Halsey, Andrea, Wang, Marie Xun, Törnroth-Horsefield, Susanna, Conner, Alex C, Badaut, Jerome, Iliff, Jeffrey J, Bill, Roslyn M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Update
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088512/ https://www.ncbi.nlm.nih.gov/pubmed/34499128 http://dx.doi.org/10.1093/brain/awab311

Ejemplares similares

Molecular mechanisms governing aquaporin relocalisation
por: Markou, Andrea, et al.
Publicado: (2022)

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
por: Kitchen, Philip, et al.
Publicado: (2020)

Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel
por: Kitchen, Philip, et al.
Publicado: (2015)

High-yield overproduction and purification of human aquaporins from Pichia pastoris
por: Al-Jubair, Tamim, et al.
Publicado: (2022)

Assessing water permeability of aquaporins in a proteoliposome-based stopped-flow setup
por: Steffen, Jonas Hyld, et al.
Publicado: (2022)

Characterization of human aquaporin protein-protein interactions using microscale thermophoresis (MST)
por: Al-Jubair, Tamim, et al.
Publicado: (2022)

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways
por: Kitchen, Philip, et al.
Publicado: (2015)

Water channel pore size determines exclusion properties but not solute selectivity
por: Kitchen, Philip, et al.
Publicado: (2019)

Calcein Fluorescence Quenching to Measure Plasma Membrane Water Flux in Live Mammalian Cells
por: Kitchen, Philip, et al.
Publicado: (2020)

Inhibitors of Mammalian Aquaporin Water Channels
por: Abir-Awan, Mohammed, et al.
Publicado: (2019)

Phosphorylation-Dependent Regulation of Mammalian Aquaporins
por: Nesverova, Veronika, et al.
Publicado: (2019)

Aquaporin Protein-Protein Interactions
por: Roche, Jennifer Virginia, et al.
Publicado: (2017)

Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)‐ and calmodulin‐mediated mechanism
por: Salman, Mootaz M., et al.
Publicado: (2017)

Signaling Mechanisms and Pharmacological Modulators Governing Diverse Aquaporin Functions in Human Health and Disease
por: Wagner, Kim, et al.
Publicado: (2022)

Structural Determinants of Oligomerization of the Aquaporin-4 Channel
por: Kitchen, Philip, et al.
Publicado: (2016)

Rapid Aquaporin Translocation Regulates Cellular Water Flow: MECHANISM OF HYPOTONICITY-INDUCED SUBCELLULAR LOCALIZATION OF AQUAPORIN 1 WATER CHANNEL
por: Conner, Matthew T., et al.
Publicado: (2012)

Aquaporins and Their Regulation after Spinal Cord Injury
por: Halsey, Andrea M., et al.
Publicado: (2018)

Insight into the Mammalian Aquaporin Interactome
por: Törnroth-Horsefield, Susanna, et al.
Publicado: (2022)

Focused ultrasound guided relocation of kidney stones
por: Abrol, Nitin, et al.
Publicado: (2015)

Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus
por: Hagströmer, Carl Johan, et al.
Publicado: (2023)

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia
por: Salman, Mootaz M., et al.
Publicado: (2017)

Apoptosis regulation by subcellular relocation of caspases
por: Prokhorova, Evgeniia A., et al.
Publicado: (2018)

High-resolution structure of a fish aquaporin reveals a novel extracellular fold
por: Zeng, Jiao, et al.
Publicado: (2022)

Aquaporin 4: a player in cerebral edema and neuroinflammation
por: Fukuda, Andrew M, et al.
Publicado: (2012)

Protein Subcellular Relocalization of Duplicated Genes in Arabidopsis
por: Liu, Shao-Lun, et al.
Publicado: (2014)

Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases
por: Salman, Mootaz M., et al.
Publicado: (2021)

Cell-free production and characterisation of human uncoupling protein 1–3
por: Rebuffet, Etienne, et al.
Publicado: (2017)

Protein Subcellular Relocalization in the Evolution of Yeast Singleton and Duplicate Genes
por: Qian, Wenfeng, et al.
Publicado: (2009)

Protein Subcellular Relocalization Increases the Retention of Eukaryotic Duplicate Genes
por: Byun, S. Ashley, et al.
Publicado: (2013)

Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo
por: Jang, SoRi, et al.
Publicado: (2021)

Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA-MB-231 breast cancer cell line
por: Arif, Muhammad, et al.
Publicado: (2018)

Comparative study of human mitochondrial proteome reveals extensive protein subcellular relocalization after gene duplications
por: Wang, Xiujuan, et al.
Publicado: (2009)

Structural Insights into AQP2 Targeting to Multivesicular Bodies
por: Roche, Jennifer Virginia, et al.
Publicado: (2019)

Caveolin-1 Regulates Perivascular Aquaporin-4 Expression After Cerebral Ischemia
por: Filchenko, Irina, et al.
Publicado: (2020)

Promoting Recruitment using Information Management Efficiently (PRIME): statistical analysis plan for a stepped wedge cluster randomised trial within the REstart or STop Antithrombotics Randomised Trial (RESTART)
por: Parker, Richard A., et al.
Publicado: (2017)

Mechanisms Underlying Aquaporin-4 Subcellular Mislocalization in Epilepsy
por: Szu, Jenny I., et al.
Publicado: (2022)

Statistical analysis plan for the PlAtelet Transfusion in Cerebral Haemorrhage (PATCH) trial: a multicentre randomised controlled trial
por: Baharoglu, M. Irem, et al.
Publicado: (2016)

The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: statistical analysis plan for a randomised controlled trial
por: Al-Shahi Salman, Rustam, et al.
Publicado: (2019)

Characterization of Leishmania donovani Aquaporins Shows Presence of Subcellular Aquaporins Similar to Tonoplast Intrinsic Proteins of Plants
por: Biyani, Neha, et al.
Publicado: (2011)

Salt-induced subcellular kinase relocation and seedling susceptibility caused by overexpression of Medicago SIMKK in Arabidopsis
por: Ovečka, Miroslav, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_mo0pauh55m98i74fc5irfpck0g