Cargando…
Chemoenzymatic synthesis of polypeptides in neat 1,1,1,2-tetrafluoroethane solvent
Chemoenzymatic polypeptide synthesis offers several advantages over chemical or other biological routes, however, the use of aqueous-based media suffers from reverse hydrolysis reactions that challenge peptide chain propagation. Herein, the protease from subtilisin Carlsberg biocatalyzed the synthes...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088702/ https://www.ncbi.nlm.nih.gov/pubmed/35558459 http://dx.doi.org/10.1039/c8ra06657d |