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Chemoenzymatic synthesis of polypeptides in neat 1,1,1,2-tetrafluoroethane solvent

Chemoenzymatic polypeptide synthesis offers several advantages over chemical or other biological routes, however, the use of aqueous-based media suffers from reverse hydrolysis reactions that challenge peptide chain propagation. Herein, the protease from subtilisin Carlsberg biocatalyzed the synthes...

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Detalles Bibliográficos
Autores principales: Aguirre-Díaz, Isabel S., Montiel, Carmina, Bustos-Jaimes, Ismael, Medina-Gonzalez, Yaocihuatl, Tecante, Alberto, Gimeno, Miquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088702/
https://www.ncbi.nlm.nih.gov/pubmed/35558459
http://dx.doi.org/10.1039/c8ra06657d