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Chemoenzymatic synthesis of polypeptides in neat 1,1,1,2-tetrafluoroethane solvent
Chemoenzymatic polypeptide synthesis offers several advantages over chemical or other biological routes, however, the use of aqueous-based media suffers from reverse hydrolysis reactions that challenge peptide chain propagation. Herein, the protease from subtilisin Carlsberg biocatalyzed the synthes...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088702/ https://www.ncbi.nlm.nih.gov/pubmed/35558459 http://dx.doi.org/10.1039/c8ra06657d |