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Unorthodox synthesis, biological activity and DFT studies of novel and multifunctionalized naphthoxocine derivatives

A new promising protocol has been developed for the synthesis of scarce oxocine derivatives 3a–e and 6 through addition of amine-based nucleophiles such as hydroxylamine hydrochloride, primary amine and hydrazide to chromonylidene benzothiazol-2-ylacetonitrile 2 in refluxing dioxane under metal free...

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Detalles Bibliográficos
Autores principales: Abozeid, Mohamed Ahmed, El-Sawi, Aya Atef, Elmorsy, Mohamed Ramadan, Abdelmoteleb, Mohamed, Hassan Abdel-Rahman, Abdel-Rahman, Ibrahim El-Desoky, El-Sayed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088745/
https://www.ncbi.nlm.nih.gov/pubmed/35558993
http://dx.doi.org/10.1039/c9ra05154f