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Chemical stability and interactions in a new antihypertensive mixture containing indapamide and dihydralazine using FT-IR, HPLC and LC-MS methods

Indapamide and dihydralazine can be combined in fixed-dose formulations because of their complementary actions against hypertension. On the other hand, combined formulations present the problem of chemical interactions between the active ingredients, e.g. accelerated degradation of constituents or g...

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Detalles Bibliográficos
Autores principales: Gumieniczek, Anna, Galeza, Justyna, Berecka, Anna, Mroczek, Tomasz, Wojtanowski, Krzysztof, Lipska, Katarzyna, Skarbek, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088757/
https://www.ncbi.nlm.nih.gov/pubmed/35558458
http://dx.doi.org/10.1039/c8ra06707d

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