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Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case

This work presents a novel methodology for systematically processing the time series that report the number of positive, recovered and deceased cases from a viral epidemic, such as Covid-19. The main objective is to unveil the evolution of the number of real infected people, and consequently to pred...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IEEE 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088803/
https://www.ncbi.nlm.nih.gov/pubmed/33657005
http://dx.doi.org/10.1109/JBHI.2021.3063106
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description This work presents a novel methodology for systematically processing the time series that report the number of positive, recovered and deceased cases from a viral epidemic, such as Covid-19. The main objective is to unveil the evolution of the number of real infected people, and consequently to predict the peak of the epidemic and subsequent evolution. For this purpose, an original nonlinear model relating the raw data with the time-varying geometric ratio of infected people is elaborated, and a Kalman Filter is used to estimate the involved state variables. A hypothetical simulated case is used to show the adequacy and limitations of the proposed method. Then, several countries, including China, South Korea, Italy, Spain, U.K. and the USA, are tested to illustrate its behavior when real-life data are processed. The results obtained clearly show the beneficial effect of the severe lockdowns imposed by many countries worldwide, but also that the softer social distancing measures adopted afterwards have been almost always insufficient to prevent the subsequent virus waves.
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spelling pubmed-90888032022-05-13 Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case IEEE J Biomed Health Inform Article This work presents a novel methodology for systematically processing the time series that report the number of positive, recovered and deceased cases from a viral epidemic, such as Covid-19. The main objective is to unveil the evolution of the number of real infected people, and consequently to predict the peak of the epidemic and subsequent evolution. For this purpose, an original nonlinear model relating the raw data with the time-varying geometric ratio of infected people is elaborated, and a Kalman Filter is used to estimate the involved state variables. A hypothetical simulated case is used to show the adequacy and limitations of the proposed method. Then, several countries, including China, South Korea, Italy, Spain, U.K. and the USA, are tested to illustrate its behavior when real-life data are processed. The results obtained clearly show the beneficial effect of the severe lockdowns imposed by many countries worldwide, but also that the softer social distancing measures adopted afterwards have been almost always insufficient to prevent the subsequent virus waves. IEEE 2021-03-03 /pmc/articles/PMC9088803/ /pubmed/33657005 http://dx.doi.org/10.1109/JBHI.2021.3063106 Text en This article is free to access and download, along with rights for full text and data mining, re-use and analysis.
spellingShingle Article
Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case
title Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case
title_full Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case
title_fullStr Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case
title_full_unstemmed Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case
title_short Monitoring and Tracking the Evolution of a Viral Epidemic Through Nonlinear Kalman Filtering: Application to the COVID-19 Case
title_sort monitoring and tracking the evolution of a viral epidemic through nonlinear kalman filtering: application to the covid-19 case
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088803/
https://www.ncbi.nlm.nih.gov/pubmed/33657005
http://dx.doi.org/10.1109/JBHI.2021.3063106
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