Identification of a Trm732 Motif Required for 2′-O-methylation of the tRNA Anticodon Loop by Trm7

[Image: see text] Posttranscriptional tRNA modifications are essential for proper gene expression, and defects in the enzymes that perform tRNA modifications are associated with numerous human disorders. Throughout eukaryotes, 2′-O-methylation of residues 32 and 34 of the anticodon loop of tRNA is i...

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Autores principales: Funk, Holly M., DiVita, Daisy J., Sizemore, Hannah E., Wehrle, Kendal, Miller, Catherine L. W., Fraley, Morgan E., Mullins, Alex K., Guy, Adrian R., Phizicky, Eric M., Guy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088939/
https://www.ncbi.nlm.nih.gov/pubmed/35559166
http://dx.doi.org/10.1021/acsomega.1c07231

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