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Regenerative Medicine Therapy in Malaysia: An Update

Regenerative medicine is a field in medicine that relates to the ability to correct congenital anomalies and to repair or replace tissues and organs that have been destroyed by age, disease, or trauma. To date, promising preclinical and clinical data supported the possibility of using regenerative m...

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Autores principales: Imran, Siti A. M., M. Hamizul, M. Haikal Aiman, Khairul Bariah, Ahmad Amin Noordin, Wan Kamarul Zaman, Wan Safwani, Nordin, Fazlina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089164/
https://www.ncbi.nlm.nih.gov/pubmed/35557868
http://dx.doi.org/10.3389/fbioe.2022.789644
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author Imran, Siti A. M.
M. Hamizul, M. Haikal Aiman
Khairul Bariah, Ahmad Amin Noordin
Wan Kamarul Zaman, Wan Safwani
Nordin, Fazlina
author_facet Imran, Siti A. M.
M. Hamizul, M. Haikal Aiman
Khairul Bariah, Ahmad Amin Noordin
Wan Kamarul Zaman, Wan Safwani
Nordin, Fazlina
author_sort Imran, Siti A. M.
collection PubMed
description Regenerative medicine is a field in medicine that relates to the ability to correct congenital anomalies and to repair or replace tissues and organs that have been destroyed by age, disease, or trauma. To date, promising preclinical and clinical data supported the possibility of using regenerative medicine to treat both chronic diseases and acute insults, as well as maladies affecting a wide range of organ systems and contexts, such as dermal wounds, cardiovascular diseases and traumas, cancer treatments, and more. One of the regenerative medicine therapies that have been used widely is stem cells. Stem cells, especially mesenchymal and hematopoietic stem cells, play an important role in treating chronic diseases, such as leukemia, bone marrow, autoimmune disease, and urinary problems. Despite considerable advancements in stem cell biology, their applications are limited by ethical concerns about embryonic stem cells, tumor development, and rejection. Nevertheless, many of these constraints, are being overcome, which could lead to significant advancements in disease management. This review discusses the current developments and advancements of regenerative medicine therapy (RMT) advancements in Malaysia compared to other Asian countries. The limitations in the application of RMT are also highlighted.
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spelling pubmed-90891642022-05-11 Regenerative Medicine Therapy in Malaysia: An Update Imran, Siti A. M. M. Hamizul, M. Haikal Aiman Khairul Bariah, Ahmad Amin Noordin Wan Kamarul Zaman, Wan Safwani Nordin, Fazlina Front Bioeng Biotechnol Bioengineering and Biotechnology Regenerative medicine is a field in medicine that relates to the ability to correct congenital anomalies and to repair or replace tissues and organs that have been destroyed by age, disease, or trauma. To date, promising preclinical and clinical data supported the possibility of using regenerative medicine to treat both chronic diseases and acute insults, as well as maladies affecting a wide range of organ systems and contexts, such as dermal wounds, cardiovascular diseases and traumas, cancer treatments, and more. One of the regenerative medicine therapies that have been used widely is stem cells. Stem cells, especially mesenchymal and hematopoietic stem cells, play an important role in treating chronic diseases, such as leukemia, bone marrow, autoimmune disease, and urinary problems. Despite considerable advancements in stem cell biology, their applications are limited by ethical concerns about embryonic stem cells, tumor development, and rejection. Nevertheless, many of these constraints, are being overcome, which could lead to significant advancements in disease management. This review discusses the current developments and advancements of regenerative medicine therapy (RMT) advancements in Malaysia compared to other Asian countries. The limitations in the application of RMT are also highlighted. Frontiers Media S.A. 2022-04-26 /pmc/articles/PMC9089164/ /pubmed/35557868 http://dx.doi.org/10.3389/fbioe.2022.789644 Text en Copyright © 2022 Imran, M. Hamizul, Khairul Bariah, Wan Kamarul Zaman and Nordin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Imran, Siti A. M.
M. Hamizul, M. Haikal Aiman
Khairul Bariah, Ahmad Amin Noordin
Wan Kamarul Zaman, Wan Safwani
Nordin, Fazlina
Regenerative Medicine Therapy in Malaysia: An Update
title Regenerative Medicine Therapy in Malaysia: An Update
title_full Regenerative Medicine Therapy in Malaysia: An Update
title_fullStr Regenerative Medicine Therapy in Malaysia: An Update
title_full_unstemmed Regenerative Medicine Therapy in Malaysia: An Update
title_short Regenerative Medicine Therapy in Malaysia: An Update
title_sort regenerative medicine therapy in malaysia: an update
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089164/
https://www.ncbi.nlm.nih.gov/pubmed/35557868
http://dx.doi.org/10.3389/fbioe.2022.789644
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