Synthesis of six-membered spirooxindoles via a chiral Brønsted acid-catalyzed asymmetric intramolecular Friedel–Crafts reaction

By means of the direct condensation of N-aminoethylpyrroles and isatins, followed by a chiral phosphoric acid-catalyzed asymmetric intramolecular Friedel-Crafts reaction, a new class of valuable chiral 3′,4′-dihydro-2′H-spiro[indoline-3,1′-pyrrolo[1,2-a]pyrazin]-2-ones bearing a quaternary carbon st...

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Detalles Bibliográficos
Autores principales: Chen, Hui-Xuan, Zhang, Yaqi, Zhang, Yuyang, He, Xuefeng, Zhang, Zhen-Wei, Liang, Hao, He, Wenhuan, Jiang, Xiaoding, Chen, Xiangmeng, Qiu, Liqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089239/
https://www.ncbi.nlm.nih.gov/pubmed/35557774
http://dx.doi.org/10.1039/c8ra06710d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089239/
https://www.ncbi.nlm.nih.gov/pubmed/35557774
http://dx.doi.org/10.1039/c8ra06710d

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