A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities

A second generation polyphosphoric acid-mediated one-pot three-component synthesis of indoloquinoline scaffold is developed. This improved version of the process involves electrophilically activated nitroalkanes for the installation of strategic C–C and C–N bonds and ring C assembly. This modificati...

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Detalles Bibliográficos
Autores principales: Aksenov, Nicolai A., Aksenov, Alexander V., Kornienko, Alexander, De Carvalho, Annelise, Mathieu, Véronique, Aksenov, Dmitrii A., Ovcharov, Sergei N., Griaznov, Georgii D., Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089289/
https://www.ncbi.nlm.nih.gov/pubmed/35558925
http://dx.doi.org/10.1039/c8ra08155g

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