Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway

Doxorubicin (DOX) is limited in clinical application because of its cardiotoxicity. Oxidative stress and apoptosis are crucial in DOX-induced cardiac injury. Dimethyl fumarate (DMF) is an FDA-approved oral drug with powerful effects to reduce oxidative stress and apoptosis through the Nrf2 pathway....

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Detalles Bibliográficos
Autores principales: Hu, Xiaoliang, Li, Cheng, Wang, Qian, Wei, Zhixing, Chen, Taizhong, Wang, Yuepeng, Li, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089305/
https://www.ncbi.nlm.nih.gov/pubmed/35559248
http://dx.doi.org/10.3389/fphar.2022.872057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089305/
https://www.ncbi.nlm.nih.gov/pubmed/35559248
http://dx.doi.org/10.3389/fphar.2022.872057

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