Cargando…
Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney
Cutaneous lupus is commonly present in patients with systemic lupus erythematosus (SLE). T cells have been strongly suspected to contribute to the pathology of cutaneous lupus; however, our understanding of the relevant T cell phenotypes and functions remains incomplete. Here, we present a detailed...
Autores principales: | Dunlap, Garrett S., Billi, Allison C., Xing, Xianying, Ma, Feiyang, Maz, Mitra P., Tsoi, Lam C., Wasikowski, Rachael, Hodgin, Jeffrey B., Gudjonsson, Johann E., Kahlenberg, J. Michelle, Rao, Deepak A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089784/ https://www.ncbi.nlm.nih.gov/pubmed/35290245 http://dx.doi.org/10.1172/jci.insight.156341 |
Ejemplares similares
-
Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes
por: Merleev, Alexander A., et al.
Publicado: (2022) -
Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis
por: Roth-Carter, Quinn R., et al.
Publicado: (2023) -
Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin
por: Wiedemann, Julie, et al.
Publicado: (2023) -
IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions
por: Tsoi, Lam C., et al.
Publicado: (2020) -
Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells
por: Heesters, Balthasar A., et al.
Publicado: (2021)