Nucleotide substitutions in the mexR, nalC and nalD regulator genes of the MexAB-OprM efflux pump are maintained in Pseudomonas aeruginosa genetic lineages

Pseudomonas aeruginosa has different resistant mechanisms including the constitutive MexAB-OprM efflux pump. Single nucleotide polymorphisms (SNPs) in the mexR, nalC, and nalD repressors of this efflux pump can contribute to antimicrobial resistance; however, it is unknown whether these changes are...

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Detalles Bibliográficos
Autores principales: Aguilar-Rodea, Pamela, Zúñiga, Gerardo, Cerritos, René, Rodríguez-Espino, Benjamín Antonio, Gomez-Ramirez, Uriel, Nolasco-Romero, Carolina G., López-Marceliano, Beatriz, Rodea, Gerardo E., Mendoza-Elizalde, Sandra, Reyes-López, Alfonso, Olivares Clavijo, Héctor, Vigueras Galindo, Juan Carlos, Velázquez-Guadarrama, Norma, Rosas-Pérez, Irma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089866/
https://www.ncbi.nlm.nih.gov/pubmed/35536836
http://dx.doi.org/10.1371/journal.pone.0266742

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