COX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis

Giardia duodenalis, the causative agent of giardiasis, is among the most important causes of waterborne diarrheal diseases around the world. Giardia infection may persist over extended periods with intestinal inflammation, although minimal. Cyclooxygenase (COX)-2 is well known as an important induce...

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Detalles Bibliográficos
Autores principales: Zhao, Yudan, Yang, Yongwu, Liu, Min, Qin, Xuening, Yu, Xiran, Zhao, Huimin, Li, Xiaoyun, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089906/
https://www.ncbi.nlm.nih.gov/pubmed/35482821
http://dx.doi.org/10.1371/journal.pntd.0010402

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