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The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication

RSK1, an essential cellular kinase for Kaposi’s sarcoma-associated herpesvirus (KSHV) replication, is highly phosphorylated and SUMOylated during KSHV lytic cycle, which determine the substrate phosphorylation and specificity of RSK1, respectively. However, the SUMO E3 ligase responsible for attachi...

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Detalles Bibliográficos
Autores principales:	Liu, Zhenshan, Wang, Xin, Liu, Chengrong, Deng, Hongying, Li, Wenshu, Wang, Xiaoqian, Xu, Xue, Xiao, Maggie Z. X., Wang, Chunxia, Zhang, Yucai, Fu, Joyce, Zhu, Fanxiu, Liang, Qiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089915/ https://www.ncbi.nlm.nih.gov/pubmed/35482828 http://dx.doi.org/10.1371/journal.ppat.1010504

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