Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report

Multiple sclerosis (MS) is a neurologic disease caused by a chronic autoimmune process resulting in the demyelination of axons within the central nervous system. MS occurs through combined genetic susceptibility and environmental triggers. MS relapses (MSR) are characterized by acute inflammatory re...

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Autores principales: Al-Midfai, Younus, Kujundzic, Winy, Uppal, Simrun, Oakes, Darby, Giezy, Sardinas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090220/
https://www.ncbi.nlm.nih.gov/pubmed/35547449
http://dx.doi.org/10.7759/cureus.24017
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author Al-Midfai, Younus
Kujundzic, Winy
Uppal, Simrun
Oakes, Darby
Giezy, Sardinas
author_facet Al-Midfai, Younus
Kujundzic, Winy
Uppal, Simrun
Oakes, Darby
Giezy, Sardinas
author_sort Al-Midfai, Younus
collection PubMed
description Multiple sclerosis (MS) is a neurologic disease caused by a chronic autoimmune process resulting in the demyelination of axons within the central nervous system. MS occurs through combined genetic susceptibility and environmental triggers. MS relapses (MSR) are characterized by acute inflammatory reactions and symptoms. Here we present a novel case of MSR following the second dose of the Johnson & Johnson coronavirus disease 2019 (COVID-19) vaccine (Johnson & Johnson, New Brunswick, New Jersey, United States), presenting with paresthesias and left foot deficit. Additional research and studies are necessary to explore the relationship of COVID-19 vaccinations with MSR.
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spelling pubmed-90902202022-05-10 Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report Al-Midfai, Younus Kujundzic, Winy Uppal, Simrun Oakes, Darby Giezy, Sardinas Cureus Internal Medicine Multiple sclerosis (MS) is a neurologic disease caused by a chronic autoimmune process resulting in the demyelination of axons within the central nervous system. MS occurs through combined genetic susceptibility and environmental triggers. MS relapses (MSR) are characterized by acute inflammatory reactions and symptoms. Here we present a novel case of MSR following the second dose of the Johnson & Johnson coronavirus disease 2019 (COVID-19) vaccine (Johnson & Johnson, New Brunswick, New Jersey, United States), presenting with paresthesias and left foot deficit. Additional research and studies are necessary to explore the relationship of COVID-19 vaccinations with MSR. Cureus 2022-04-10 /pmc/articles/PMC9090220/ /pubmed/35547449 http://dx.doi.org/10.7759/cureus.24017 Text en Copyright © 2022, Al-Midfai et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Al-Midfai, Younus
Kujundzic, Winy
Uppal, Simrun
Oakes, Darby
Giezy, Sardinas
Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
title Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
title_full Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
title_fullStr Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
title_full_unstemmed Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
title_short Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
title_sort acute multiple sclerosis exacerbation after vaccination with the johnson & johnson covid-19 vaccine: novel presentation and first documented case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090220/
https://www.ncbi.nlm.nih.gov/pubmed/35547449
http://dx.doi.org/10.7759/cureus.24017
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