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Temporary antimetabolite treatment hold boosts SARS-CoV-2 vaccination–specific humoral and cellular immunity in kidney transplant recipients

Transplant recipients exhibit an impaired protective immunity after SARS-CoV-2 vaccination, potentially caused by mycophenolate (MPA) immunosuppression. Recent data from patients with autoimmune disorders suggest that temporary MPA hold might greatly improve booster vaccination outcomes. We applied...

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Detalles Bibliográficos
Autores principales: Schrezenmeier, Eva, Rincon-Arevalo, Hector, Jens, Annika, Stefanski, Ana-Luisa, Hammett, Charlotte, Osmanodja, Bilgin, Koch, Nadine, Zukunft, Bianca, Beck, Julia, Oellerich, Michael, Proß, Vanessa, Stahl, Carolin, Choi, Mira, Bachmann, Friederike, Liefeldt, Lutz, Glander, Petra, Schütz, Ekkehard, Bornemann-Kolatzki, Kirsten, López del Moral, Covadonga, Schrezenmeier, Hubert, Ludwig, Carolin, Jahrsdörfer, Bernd, Eckardt, Kai-Uwe, Lachmann, Nils, Kotsch, Katja, Dörner, Thomas, Halleck, Fabian, Sattler, Arne, Budde, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090237/
https://www.ncbi.nlm.nih.gov/pubmed/35349490
http://dx.doi.org/10.1172/jci.insight.157836