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Antibody-dependent cellular cytotoxicity responses and susceptibility influence HIV-1 mother-to-child transmission

HIV-1 vaccine efforts are primarily directed toward eliciting neutralizing antibodies (nAbs). However, vaccine trials and mother-to-child natural history cohort investigations indicate that antibody-dependent cellular cytotoxicity (ADCC), not nAbs, correlate with prevention. The ADCC characteristics...

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Detalles Bibliográficos
Autores principales:	Thomas, Allison S., Coote, Carolyn, Moreau, Yvetane, Isaac, John E., Ewing, Alexander C., Kourtis, Athena P., Sagar, Manish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090239/ https://www.ncbi.nlm.nih.gov/pubmed/35324477 http://dx.doi.org/10.1172/jci.insight.159435

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