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Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression

BACKGROUND: Immune cell profiling of primary and metastatic CNS tumors has been focused on the tumor, not the tumor microenvironment (TME), or has been analyzed via biopsies. METHODS: En bloc resections of gliomas (n = 10) and lung metastases (n = 10) were analyzed via tissue segmentation and high-d...

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Detalles Bibliográficos
Autores principales:	Najem, Hinda, Ott, Martina, Kassab, Cynthia, Rao, Arvind, Rao, Ganesh, Marisetty, Anantha, Sonabend, Adam M., Horbinski, Craig, Verhaak, Roel, Shankar, Anand, Krishnan, Santhoshi N., Varn, Frederick S., Arrieta, Víctor A., Gupta, Pravesh, Ferguson, Sherise D., Huse, Jason T., Fuller, Gregory N., Long, James P., Winkowski, Daniel E., Freiberg, Ben A., James, Charles David, Platanias, Leonidas C., Lesniak, Maciej S., Burks, Jared K., Heimberger, Amy B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090258/ https://www.ncbi.nlm.nih.gov/pubmed/35316217 http://dx.doi.org/10.1172/jci.insight.157612

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