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Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study
OBJECTIVE: To compare the number of contacts to general practice across 11 types of abdominal cancer in the 12 months preceding a diagnosis. DESIGN: Nationwide register study. SETTING: Danish general practice. SUBJECTS: Forty-seven thousand eight hundred and ninety-eight patients diagnosed with oeso...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090419/ https://www.ncbi.nlm.nih.gov/pubmed/35362365 http://dx.doi.org/10.1080/02813432.2022.2057054 |
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author | Jessen, Nanna Holt Jensen, Henry Falborg, Alina Zalounina Glerup, Henning Gronbaek, Henning Vedsted, Peter |
author_facet | Jessen, Nanna Holt Jensen, Henry Falborg, Alina Zalounina Glerup, Henning Gronbaek, Henning Vedsted, Peter |
author_sort | Jessen, Nanna Holt |
collection | PubMed |
description | OBJECTIVE: To compare the number of contacts to general practice across 11 types of abdominal cancer in the 12 months preceding a diagnosis. DESIGN: Nationwide register study. SETTING: Danish general practice. SUBJECTS: Forty-seven thousand eight hundred and ninety-eight patients diagnosed with oesophageal, gastric, colon, rectal, liver, gall bladder/biliary tract, pancreatic, endometrial, ovarian, kidney or bladder cancer in 2014–2018. MAIN OUTCOME MEASURES: Monthly contact rates and incidence rate ratios (IRRs) of daytime face-to-face, email and telephone consultations in general practice across different abdominal cancers. The analyses were conducted for each sex and adjusted for age, comorbidity, marital status and education. RESULTS: Compared to women with colon cancer, women with rectal cancer had the lowest number of contacts to general practice (IRR 12 months pre-diagnostic (IRR(–12))=0.86 (95% CI: 0.80–0.92); IRR 1 month pre-diagnostic (IRR(–1))=0.85 (95% CI: 0.81–0.89)), whereas women with liver (IRR(–12)=1.23 (95% CI: 1.09–1.38); IRR(–1)=1.11 (95% CI: 1.02–1.20)), pancreatic (IRR(–12)=1.08 (95% CI: 1.01–1.16); IRR(1)=1.52 (95% CI: 1.45–1.58)) and kidney cancer (IRR(–12)=1.14 (95% CI: 1.05–1.23); IRR(–1)=1.18 (95% CI: 1.12–1.24)) had the highest number of contacts. Men showed similar patterns. From seven months pre-diagnostic, an increase in contacts to general practice was seen in bladder cancer patients, particularly women, compared to colon cancer. CONCLUSIONS: Using pre-diagnostic contact rates unveiled that liver, pancreatic, kidney and bladder cancers had a higher and more prolonged use of general practice. This may suggest missed opportunities of diagnosing cancer. Thus, pre-diagnostic contact rates may indicate symptoms and signs for cancer that need further research to ensure early cancer diagnosis. KEY POINTS: The majority of cancer patients attend their general practitioner (GP) before diagnosis; however, little is known about the use of general practice across different abdominal cancers. This study suggests that a potential exists to detect some abdominal cancers at an earlier point in time. The contact patterns in general practice seem to be shaped by the degree of diagnostic difficulty. GPs may need additional diagnostic opportunities to identify abdominal cancer in symptomatic patients. |
format | Online Article Text |
id | pubmed-9090419 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-90904192022-05-11 Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study Jessen, Nanna Holt Jensen, Henry Falborg, Alina Zalounina Glerup, Henning Gronbaek, Henning Vedsted, Peter Scand J Prim Health Care Original Articles OBJECTIVE: To compare the number of contacts to general practice across 11 types of abdominal cancer in the 12 months preceding a diagnosis. DESIGN: Nationwide register study. SETTING: Danish general practice. SUBJECTS: Forty-seven thousand eight hundred and ninety-eight patients diagnosed with oesophageal, gastric, colon, rectal, liver, gall bladder/biliary tract, pancreatic, endometrial, ovarian, kidney or bladder cancer in 2014–2018. MAIN OUTCOME MEASURES: Monthly contact rates and incidence rate ratios (IRRs) of daytime face-to-face, email and telephone consultations in general practice across different abdominal cancers. The analyses were conducted for each sex and adjusted for age, comorbidity, marital status and education. RESULTS: Compared to women with colon cancer, women with rectal cancer had the lowest number of contacts to general practice (IRR 12 months pre-diagnostic (IRR(–12))=0.86 (95% CI: 0.80–0.92); IRR 1 month pre-diagnostic (IRR(–1))=0.85 (95% CI: 0.81–0.89)), whereas women with liver (IRR(–12)=1.23 (95% CI: 1.09–1.38); IRR(–1)=1.11 (95% CI: 1.02–1.20)), pancreatic (IRR(–12)=1.08 (95% CI: 1.01–1.16); IRR(1)=1.52 (95% CI: 1.45–1.58)) and kidney cancer (IRR(–12)=1.14 (95% CI: 1.05–1.23); IRR(–1)=1.18 (95% CI: 1.12–1.24)) had the highest number of contacts. Men showed similar patterns. From seven months pre-diagnostic, an increase in contacts to general practice was seen in bladder cancer patients, particularly women, compared to colon cancer. CONCLUSIONS: Using pre-diagnostic contact rates unveiled that liver, pancreatic, kidney and bladder cancers had a higher and more prolonged use of general practice. This may suggest missed opportunities of diagnosing cancer. Thus, pre-diagnostic contact rates may indicate symptoms and signs for cancer that need further research to ensure early cancer diagnosis. KEY POINTS: The majority of cancer patients attend their general practitioner (GP) before diagnosis; however, little is known about the use of general practice across different abdominal cancers. This study suggests that a potential exists to detect some abdominal cancers at an earlier point in time. The contact patterns in general practice seem to be shaped by the degree of diagnostic difficulty. GPs may need additional diagnostic opportunities to identify abdominal cancer in symptomatic patients. Taylor & Francis 2022-04-01 /pmc/articles/PMC9090419/ /pubmed/35362365 http://dx.doi.org/10.1080/02813432.2022.2057054 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Jessen, Nanna Holt Jensen, Henry Falborg, Alina Zalounina Glerup, Henning Gronbaek, Henning Vedsted, Peter Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
title | Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
title_full | Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
title_fullStr | Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
title_full_unstemmed | Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
title_short | Contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
title_sort | contacts to general practice in the 12 months preceding a diagnosis of an abdominal cancer: a national register-based cohort study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090419/ https://www.ncbi.nlm.nih.gov/pubmed/35362365 http://dx.doi.org/10.1080/02813432.2022.2057054 |
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