Multicomponent synthesis of pyrano[2,3-c]coumarins

A base-catalyzed, pseudo-four-component reaction of 4-hydroxycoumarin, two molecules of acetone, and amine towards the synthesis of pyrano[2,3-c]coumarins is reported. The mechanism of this multicomponent reaction is proposed. The reaction is further extended to the preparation of coumarin-substitut...

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Autores principales: Hsieh, Wan-Chi, Lin, Chi-Hui, Yang, Yu-Ju, Yang, Ding-Yah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090729/
https://www.ncbi.nlm.nih.gov/pubmed/35558298
http://dx.doi.org/10.1039/c8ra06666c
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author Hsieh, Wan-Chi
Lin, Chi-Hui
Yang, Yu-Ju
Yang, Ding-Yah
author_facet Hsieh, Wan-Chi
Lin, Chi-Hui
Yang, Yu-Ju
Yang, Ding-Yah
author_sort Hsieh, Wan-Chi
collection PubMed
description A base-catalyzed, pseudo-four-component reaction of 4-hydroxycoumarin, two molecules of acetone, and amine towards the synthesis of pyrano[2,3-c]coumarins is reported. The mechanism of this multicomponent reaction is proposed. The reaction is further extended to the preparation of coumarin-substituted pyrano[2,3-c]coumarins by a base-catalyzed, pseudo four-component reaction of two molecules of 4-hydroxycoumarin and two molecules of acetone.
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spelling pubmed-90907292022-05-11 Multicomponent synthesis of pyrano[2,3-c]coumarins Hsieh, Wan-Chi Lin, Chi-Hui Yang, Yu-Ju Yang, Ding-Yah RSC Adv Chemistry A base-catalyzed, pseudo-four-component reaction of 4-hydroxycoumarin, two molecules of acetone, and amine towards the synthesis of pyrano[2,3-c]coumarins is reported. The mechanism of this multicomponent reaction is proposed. The reaction is further extended to the preparation of coumarin-substituted pyrano[2,3-c]coumarins by a base-catalyzed, pseudo four-component reaction of two molecules of 4-hydroxycoumarin and two molecules of acetone. The Royal Society of Chemistry 2018-11-22 /pmc/articles/PMC9090729/ /pubmed/35558298 http://dx.doi.org/10.1039/c8ra06666c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Hsieh, Wan-Chi
Lin, Chi-Hui
Yang, Yu-Ju
Yang, Ding-Yah
Multicomponent synthesis of pyrano[2,3-c]coumarins
title Multicomponent synthesis of pyrano[2,3-c]coumarins
title_full Multicomponent synthesis of pyrano[2,3-c]coumarins
title_fullStr Multicomponent synthesis of pyrano[2,3-c]coumarins
title_full_unstemmed Multicomponent synthesis of pyrano[2,3-c]coumarins
title_short Multicomponent synthesis of pyrano[2,3-c]coumarins
title_sort multicomponent synthesis of pyrano[2,3-c]coumarins
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090729/
https://www.ncbi.nlm.nih.gov/pubmed/35558298
http://dx.doi.org/10.1039/c8ra06666c
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AT linchihui multicomponentsynthesisofpyrano23ccoumarins
AT yangyuju multicomponentsynthesisofpyrano23ccoumarins
AT yangdingyah multicomponentsynthesisofpyrano23ccoumarins

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