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Development of Low-Molecular-Weight Allosteric Agonist of Thyroid-Stimulating Hormone Receptor with Thyroidogenic Activity

To normalize the thyroid status in hypothyroidism caused by resistance to thyroid-stimulating hormone (TSH), low-molecular-weight allosteric agonists of TSH receptor can be used. A new compound ethyl-2-(4-(4-(5-amino-6-(tert-butylcarbamoyl)-2-(methylthio)thieno[2,3-d]-pyrimidine-4-yl)phenyl)-1H-1,2,...

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Detalles Bibliográficos
Autores principales:	Bakhtyukov, A. A., Derkach, K. V., Fokina, E. A., Sorokoumov, V. N., Zakharova, I. O., Bayunova, L. V., Shpakov, A. O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pleiades Publishing 2022
Materias:	Biochemistry, Biophysics, and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090882/ https://www.ncbi.nlm.nih.gov/pubmed/35538280 http://dx.doi.org/10.1134/S1607672922020016

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