LincRNA#1 knockout alone does not affect polled phenotype in cattle heterozygous for the celtic POLLED allele

A long intergenic non-coding RNA (lincRNA#1) is overexpressed in the horn bud region of polled (hornless) bovine fetuses, suggesting a potential role in horn bud suppression. Genome editing was used to test whether the absence of this sequence was associated with the horned phenotype. Two gRNAs with...

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Detalles Bibliográficos
Autores principales: Hennig, Sadie L., McNabb, Bret R., Trott, Josephine F., Van Eenennaam, Alison L., Murray, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090918/
https://www.ncbi.nlm.nih.gov/pubmed/35538091
http://dx.doi.org/10.1038/s41598-022-11669-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090918/
https://www.ncbi.nlm.nih.gov/pubmed/35538091
http://dx.doi.org/10.1038/s41598-022-11669-9

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