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LincRNA#1 knockout alone does not affect polled phenotype in cattle heterozygous for the celtic POLLED allele
A long intergenic non-coding RNA (lincRNA#1) is overexpressed in the horn bud region of polled (hornless) bovine fetuses, suggesting a potential role in horn bud suppression. Genome editing was used to test whether the absence of this sequence was associated with the horned phenotype. Two gRNAs with...
Autores principales: | Hennig, Sadie L., McNabb, Bret R., Trott, Josephine F., Van Eenennaam, Alison L., Murray, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090918/ https://www.ncbi.nlm.nih.gov/pubmed/35538091 http://dx.doi.org/10.1038/s41598-022-11669-9 |
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