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PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence
BACKGROUND: Identification of novel molecular target(s) is important for designing newer mechanistically driven approaches for the treatment of prostate cancer (PCa), which is one of the main causes of morbidity and mortality in men. In this study, we determined the role of polo‐like kinase 4 (PLK4)...
Autores principales: | Singh, Chandra K., Denu, Ryan A., Nihal, Minakshi, Shabbir, Maria, Garvey, Debra R., Huang, Wei, Iczkowski, Kenneth A., Ahmad, Nihal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090996/ https://www.ncbi.nlm.nih.gov/pubmed/35333404 http://dx.doi.org/10.1002/pros.24342 |
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