Pan-Cancer Bioinformatics Analysis of Gene UBE2C

Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression,...

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Detalles Bibliográficos
Autores principales: Yuan, Lin, Yang, Zhenyu, Zhao, Jing, Sun, Tao, Hu, Chunyu, Shen, Zhen, Yu, Guanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091452/
https://www.ncbi.nlm.nih.gov/pubmed/35571064
http://dx.doi.org/10.3389/fgene.2022.893358
Descripción
Sumario:Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.

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