Pan-Cancer Bioinformatics Analysis of Gene UBE2C

Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression,...

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Autores principales: Yuan, Lin, Yang, Zhenyu, Zhao, Jing, Sun, Tao, Hu, Chunyu, Shen, Zhen, Yu, Guanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091452/
https://www.ncbi.nlm.nih.gov/pubmed/35571064
http://dx.doi.org/10.3389/fgene.2022.893358
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author Yuan, Lin
Yang, Zhenyu
Zhao, Jing
Sun, Tao
Hu, Chunyu
Shen, Zhen
Yu, Guanying
author_facet Yuan, Lin
Yang, Zhenyu
Zhao, Jing
Sun, Tao
Hu, Chunyu
Shen, Zhen
Yu, Guanying
author_sort Yuan, Lin
collection PubMed
description Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.
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spelling pubmed-90914522022-05-12 Pan-Cancer Bioinformatics Analysis of Gene UBE2C Yuan, Lin Yang, Zhenyu Zhao, Jing Sun, Tao Hu, Chunyu Shen, Zhen Yu, Guanying Front Genet Genetics Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc. Frontiers Media S.A. 2022-04-27 /pmc/articles/PMC9091452/ /pubmed/35571064 http://dx.doi.org/10.3389/fgene.2022.893358 Text en Copyright © 2022 Yuan, Yang, Zhao, Sun, Hu, Shen and Yu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Yuan, Lin
Yang, Zhenyu
Zhao, Jing
Sun, Tao
Hu, Chunyu
Shen, Zhen
Yu, Guanying
Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_full Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_fullStr Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_full_unstemmed Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_short Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_sort pan-cancer bioinformatics analysis of gene ube2c
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091452/
https://www.ncbi.nlm.nih.gov/pubmed/35571064
http://dx.doi.org/10.3389/fgene.2022.893358
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