Iso-pencillixanthone A from a marine-derived fungus reverses multidrug resistance in cervical cancer cells through down-regulating P-gp and re-activating apoptosis

The occurrence of multidrug resistance (MDR) is highly associated with the overexpression of ATP-binding cassette (ABC) transporters, among which, P-glycoprotein (P-gp) plays one of the most important roles. Iso-pencillixanthone A (iso-PXA) is a compound isolated from the marine-derived fungus Penic...

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Detalles Bibliográficos
Autores principales: Chen, Li, Li, Xinxin, Cheng, Miaomiao, Wang, Siyuan, Zheng, Qiuhong, Liu, Qinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091570/
https://www.ncbi.nlm.nih.gov/pubmed/35559314
http://dx.doi.org/10.1039/c8ra09506j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091570/
https://www.ncbi.nlm.nih.gov/pubmed/35559314
http://dx.doi.org/10.1039/c8ra09506j

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