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Iso-pencillixanthone A from a marine-derived fungus reverses multidrug resistance in cervical cancer cells through down-regulating P-gp and re-activating apoptosis
The occurrence of multidrug resistance (MDR) is highly associated with the overexpression of ATP-binding cassette (ABC) transporters, among which, P-glycoprotein (P-gp) plays one of the most important roles. Iso-pencillixanthone A (iso-PXA) is a compound isolated from the marine-derived fungus Penic...
Autores principales: | Chen, Li, Li, Xinxin, Cheng, Miaomiao, Wang, Siyuan, Zheng, Qiuhong, Liu, Qinying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091570/ https://www.ncbi.nlm.nih.gov/pubmed/35559314 http://dx.doi.org/10.1039/c8ra09506j |
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