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Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review

Acute myocarditis is a rare but serious complication associated with mRNA-based coronavirus disease 2019 (COVID-19) vaccination. In this article, four COVID-19 mRNA vaccination induced myocarditis cases managed at our tertiary Medical Center have been discussed. Three patients had typical myocarditi...

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Autores principales: Watanabe, Keita, Ashikaga, Takashi, Maejima, Yasuhiro, Tao, Susumu, Terui, Mao, Kishigami, Tetsuya, Kaneko, Masakazu, Nakajima, Ryota, Okata, Shinichiro, Lee, Tetsumin, Horie, Tomoki, Nagase, Masashi, Nitta, Giichi, Miyazaki, Ryoichi, Nagamine, Sho, Nagata, Yasutoshi, Nozato, Toshihiro, Goya, Masahiko, Sasano, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091592/
https://www.ncbi.nlm.nih.gov/pubmed/35571222
http://dx.doi.org/10.3389/fcvm.2022.844626
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author Watanabe, Keita
Ashikaga, Takashi
Maejima, Yasuhiro
Tao, Susumu
Terui, Mao
Kishigami, Tetsuya
Kaneko, Masakazu
Nakajima, Ryota
Okata, Shinichiro
Lee, Tetsumin
Horie, Tomoki
Nagase, Masashi
Nitta, Giichi
Miyazaki, Ryoichi
Nagamine, Sho
Nagata, Yasutoshi
Nozato, Toshihiro
Goya, Masahiko
Sasano, Tetsuo
author_facet Watanabe, Keita
Ashikaga, Takashi
Maejima, Yasuhiro
Tao, Susumu
Terui, Mao
Kishigami, Tetsuya
Kaneko, Masakazu
Nakajima, Ryota
Okata, Shinichiro
Lee, Tetsumin
Horie, Tomoki
Nagase, Masashi
Nitta, Giichi
Miyazaki, Ryoichi
Nagamine, Sho
Nagata, Yasutoshi
Nozato, Toshihiro
Goya, Masahiko
Sasano, Tetsuo
author_sort Watanabe, Keita
collection PubMed
description Acute myocarditis is a rare but serious complication associated with mRNA-based coronavirus disease 2019 (COVID-19) vaccination. In this article, four COVID-19 mRNA vaccination induced myocarditis cases managed at our tertiary Medical Center have been discussed. Three patients had typical myocarditis. One patient suffered from atrioventricular block and heart failure, which required more intensive treatment, but eventually improved. Additionally, a review of cardiac magnetic resonance imaging (MRI) features related to the diagnosis of myocarditis showed that COVID-19 mRNA vaccine-associated myocarditis tend to have more late-gadolinium enhancement (LGE) accumulation in the inferior lateral wall direction. According to a report by the U.S. Centers for Disease Control and Prevention (CDC), the diagnosis of COVID-19 mRNA vaccine-associated myocarditis is based on clinical symptoms, altered myocardial enzymes, cardiac MRI finding, or histopathology. Cardiac MRI is relatively less invasive than myocardial biopsy and plays an important role in the diagnosis of myocarditis. This review may aid in the diagnosis of COVID-19 mRNA vaccine-associated myocarditis.
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spelling pubmed-90915922022-05-12 Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review Watanabe, Keita Ashikaga, Takashi Maejima, Yasuhiro Tao, Susumu Terui, Mao Kishigami, Tetsuya Kaneko, Masakazu Nakajima, Ryota Okata, Shinichiro Lee, Tetsumin Horie, Tomoki Nagase, Masashi Nitta, Giichi Miyazaki, Ryoichi Nagamine, Sho Nagata, Yasutoshi Nozato, Toshihiro Goya, Masahiko Sasano, Tetsuo Front Cardiovasc Med Cardiovascular Medicine Acute myocarditis is a rare but serious complication associated with mRNA-based coronavirus disease 2019 (COVID-19) vaccination. In this article, four COVID-19 mRNA vaccination induced myocarditis cases managed at our tertiary Medical Center have been discussed. Three patients had typical myocarditis. One patient suffered from atrioventricular block and heart failure, which required more intensive treatment, but eventually improved. Additionally, a review of cardiac magnetic resonance imaging (MRI) features related to the diagnosis of myocarditis showed that COVID-19 mRNA vaccine-associated myocarditis tend to have more late-gadolinium enhancement (LGE) accumulation in the inferior lateral wall direction. According to a report by the U.S. Centers for Disease Control and Prevention (CDC), the diagnosis of COVID-19 mRNA vaccine-associated myocarditis is based on clinical symptoms, altered myocardial enzymes, cardiac MRI finding, or histopathology. Cardiac MRI is relatively less invasive than myocardial biopsy and plays an important role in the diagnosis of myocarditis. This review may aid in the diagnosis of COVID-19 mRNA vaccine-associated myocarditis. Frontiers Media S.A. 2022-04-27 /pmc/articles/PMC9091592/ /pubmed/35571222 http://dx.doi.org/10.3389/fcvm.2022.844626 Text en Copyright © 2022 Watanabe, Ashikaga, Maejima, Tao, Terui, Kishigami, Kaneko, Nakajima, Okata, Lee, Horie, Nagase, Nitta, Miyazaki, Nagamine, Nagata, Nozato, Goya and Sasano. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Watanabe, Keita
Ashikaga, Takashi
Maejima, Yasuhiro
Tao, Susumu
Terui, Mao
Kishigami, Tetsuya
Kaneko, Masakazu
Nakajima, Ryota
Okata, Shinichiro
Lee, Tetsumin
Horie, Tomoki
Nagase, Masashi
Nitta, Giichi
Miyazaki, Ryoichi
Nagamine, Sho
Nagata, Yasutoshi
Nozato, Toshihiro
Goya, Masahiko
Sasano, Tetsuo
Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
title Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
title_full Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
title_fullStr Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
title_full_unstemmed Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
title_short Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
title_sort case report: importance of mri examination in the diagnosis and evaluation of covid-19 mrna vaccination induced myocarditis: our experience and literature review
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091592/
https://www.ncbi.nlm.nih.gov/pubmed/35571222
http://dx.doi.org/10.3389/fcvm.2022.844626
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