The Adaptive Renal Response for Volume Homeostasis During 2 Weeks of Dapagliflozin Treatment in People With Type 2 Diabetes and Preserved Renal Function on a Sodium-Controlled Diet

INTRODUCTION: Proximal tubule sodium uptake is diminished following sodium glucose cotransporter 2 (SGLT2) inhibition. We previously showed that during SGLT2 inhibition, the kidneys adapt by increasing sodium uptake at distal tubular segments, thereby maintaining body sodium balance. Despite continu...

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Detalles Bibliográficos
Autores principales: Scholtes, Rosalie A., Muskiet, Marcel H.A., van Baar, Michiel J.B., Hesp, Anne C., Greasley, Peter J., Hammarstedt, Ann, Karlsson, Cecilia, Hallow, Karen M., Danser, A.H. Jan, Heerspink, Hiddo J.L., van Raalte, Daniël H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091605/
https://www.ncbi.nlm.nih.gov/pubmed/35570989
http://dx.doi.org/10.1016/j.ekir.2022.02.023

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