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Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality

Evolutionary graph theory (EGT) investigates the Moran birth–death process constrained by graphs. Its two principal goals are to find the fixation probability and time for some initial population of mutants on the graph. The fixation probability of graphs has received considerable attention. Less is...

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Autores principales: Monk, Travis, van Schaik, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091843/
https://www.ncbi.nlm.nih.gov/pubmed/35573040
http://dx.doi.org/10.1098/rsos.220011
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author Monk, Travis
van Schaik, André
author_facet Monk, Travis
van Schaik, André
author_sort Monk, Travis
collection PubMed
description Evolutionary graph theory (EGT) investigates the Moran birth–death process constrained by graphs. Its two principal goals are to find the fixation probability and time for some initial population of mutants on the graph. The fixation probability of graphs has received considerable attention. Less is known about the distribution of fixation time. We derive clean, exact expressions for the full conditional characteristic functions (CCFs) of a close proxy to fixation and extinction times. That proxy is the number of times that the mutant population size changes before fixation or extinction. We derive these CCFs from a product martingale that we identify for an evolutionary graph with any number of partitions. The existence of that martingale only requires that the connections between those partitions are of a certain type. Our results are the first expressions for the CCFs of any proxy to fixation time on a graph with any number of partitions. The parameter dependence of our CCFs is explicit, so we can explore how they depend on graph structure. Martingales are a powerful approach to study principal problems of EGT. Their applicability is invariant to the number of partitions in a graph, so we can study entire families of graphs simultaneously.
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spelling pubmed-90918432022-05-14 Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality Monk, Travis van Schaik, André R Soc Open Sci Mathematics Evolutionary graph theory (EGT) investigates the Moran birth–death process constrained by graphs. Its two principal goals are to find the fixation probability and time for some initial population of mutants on the graph. The fixation probability of graphs has received considerable attention. Less is known about the distribution of fixation time. We derive clean, exact expressions for the full conditional characteristic functions (CCFs) of a close proxy to fixation and extinction times. That proxy is the number of times that the mutant population size changes before fixation or extinction. We derive these CCFs from a product martingale that we identify for an evolutionary graph with any number of partitions. The existence of that martingale only requires that the connections between those partitions are of a certain type. Our results are the first expressions for the CCFs of any proxy to fixation time on a graph with any number of partitions. The parameter dependence of our CCFs is explicit, so we can explore how they depend on graph structure. Martingales are a powerful approach to study principal problems of EGT. Their applicability is invariant to the number of partitions in a graph, so we can study entire families of graphs simultaneously. The Royal Society 2022-05-11 /pmc/articles/PMC9091843/ /pubmed/35573040 http://dx.doi.org/10.1098/rsos.220011 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Mathematics
Monk, Travis
van Schaik, André
Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
title Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
title_full Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
title_fullStr Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
title_full_unstemmed Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
title_short Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
title_sort martingales and the fixation time of evolutionary graphs with arbitrary dimensionality
topic Mathematics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091843/
https://www.ncbi.nlm.nih.gov/pubmed/35573040
http://dx.doi.org/10.1098/rsos.220011
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