Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs

We developed a new fluorescent peptide nucleic acid (PNA) probe, COT probe, capable of simultaneous recognition of 3′-overhang and double stranded sequences of target small interfering RNA (siRNA).

Detalles Bibliográficos
Autores principales: Tanabe, Takaaki, Sato, Takaya, Sato, Yusuke, Nishizawa, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092112/
https://www.ncbi.nlm.nih.gov/pubmed/35558768
http://dx.doi.org/10.1039/c8ra08759h
Descripción
Sumario:We developed a new fluorescent peptide nucleic acid (PNA) probe, COT probe, capable of simultaneous recognition of 3′-overhang and double stranded sequences of target small interfering RNA (siRNA).

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