Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs

We developed a new fluorescent peptide nucleic acid (PNA) probe, COT probe, capable of simultaneous recognition of 3′-overhang and double stranded sequences of target small interfering RNA (siRNA).

Detalles Bibliográficos
Autores principales: Tanabe, Takaaki, Sato, Takaya, Sato, Yusuke, Nishizawa, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092112/
https://www.ncbi.nlm.nih.gov/pubmed/35558768
http://dx.doi.org/10.1039/c8ra08759h
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author Tanabe, Takaaki
Sato, Takaya
Sato, Yusuke
Nishizawa, Seiichi
author_facet Tanabe, Takaaki
Sato, Takaya
Sato, Yusuke
Nishizawa, Seiichi
author_sort Tanabe, Takaaki
collection PubMed
description We developed a new fluorescent peptide nucleic acid (PNA) probe, COT probe, capable of simultaneous recognition of 3′-overhang and double stranded sequences of target small interfering RNA (siRNA).
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spelling pubmed-90921122022-05-11 Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs Tanabe, Takaaki Sato, Takaya Sato, Yusuke Nishizawa, Seiichi RSC Adv Chemistry We developed a new fluorescent peptide nucleic acid (PNA) probe, COT probe, capable of simultaneous recognition of 3′-overhang and double stranded sequences of target small interfering RNA (siRNA). The Royal Society of Chemistry 2018-12-18 /pmc/articles/PMC9092112/ /pubmed/35558768 http://dx.doi.org/10.1039/c8ra08759h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Tanabe, Takaaki
Sato, Takaya
Sato, Yusuke
Nishizawa, Seiichi
Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs
title Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs
title_full Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs
title_fullStr Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs
title_full_unstemmed Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs
title_short Design of a fluorogenic PNA probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering RNAs
title_sort design of a fluorogenic pna probe capable of simultaneous recognition of 3′-overhang and double-stranded sequences of small interfering rnas
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092112/
https://www.ncbi.nlm.nih.gov/pubmed/35558768
http://dx.doi.org/10.1039/c8ra08759h
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AT satoyusuke designofafluorogenicpnaprobecapableofsimultaneousrecognitionof3overhanganddoublestrandedsequencesofsmallinterferingrnas
AT nishizawaseiichi designofafluorogenicpnaprobecapableofsimultaneousrecognitionof3overhanganddoublestrandedsequencesofsmallinterferingrnas

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