Cargando…
Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment
Multisystem inflammatory syndrome in adults (MIS-A) has been reported as a rare but severe consequence of COVID-19 infection. Adult patients were more likely to present with hypotension and cardiac illness when compared with multisystem inflammatory syndrome in children. Although the exact prevalenc...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092143/ https://www.ncbi.nlm.nih.gov/pubmed/35537767 http://dx.doi.org/10.1136/bcr-2021-248520 |
_version_ | 1784705079619616768 |
---|---|
author | Rojnukoolwanich, Thitirat Kuagoolwongse, Chankanok Vibhagool, Asda Pongpirul, Krit |
author_facet | Rojnukoolwanich, Thitirat Kuagoolwongse, Chankanok Vibhagool, Asda Pongpirul, Krit |
author_sort | Rojnukoolwanich, Thitirat |
collection | PubMed |
description | Multisystem inflammatory syndrome in adults (MIS-A) has been reported as a rare but severe consequence of COVID-19 infection. Adult patients were more likely to present with hypotension and cardiac illness when compared with multisystem inflammatory syndrome in children. Although the exact prevalence of MIS-A is unknown, more cases have been observed in men and younger adults. The pathophysiology of MIS-A is also unclear, but is thought to be caused by a delayed, dysregulated immune response. Given no established guideline for treatment of MIS-A, treatment has been based on case reports. We present a case of MIS-A in a woman in her 60s who had severe hypotension, progressive dyspnoea, massive pleural effusion, hypoxaemia, thyroiditis and multiple organ failure, which dramatically improved after treatment with corticosteroid and interleukin 6 inhibitor. |
format | Online Article Text |
id | pubmed-9092143 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-90921432022-05-27 Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment Rojnukoolwanich, Thitirat Kuagoolwongse, Chankanok Vibhagool, Asda Pongpirul, Krit BMJ Case Rep Case Reports: Unusual presentation of more common disease/injury Multisystem inflammatory syndrome in adults (MIS-A) has been reported as a rare but severe consequence of COVID-19 infection. Adult patients were more likely to present with hypotension and cardiac illness when compared with multisystem inflammatory syndrome in children. Although the exact prevalence of MIS-A is unknown, more cases have been observed in men and younger adults. The pathophysiology of MIS-A is also unclear, but is thought to be caused by a delayed, dysregulated immune response. Given no established guideline for treatment of MIS-A, treatment has been based on case reports. We present a case of MIS-A in a woman in her 60s who had severe hypotension, progressive dyspnoea, massive pleural effusion, hypoxaemia, thyroiditis and multiple organ failure, which dramatically improved after treatment with corticosteroid and interleukin 6 inhibitor. BMJ Publishing Group 2022-05-10 /pmc/articles/PMC9092143/ /pubmed/35537767 http://dx.doi.org/10.1136/bcr-2021-248520 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ. |
spellingShingle | Case Reports: Unusual presentation of more common disease/injury Rojnukoolwanich, Thitirat Kuagoolwongse, Chankanok Vibhagool, Asda Pongpirul, Krit Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
title | Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
title_full | Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
title_fullStr | Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
title_full_unstemmed | Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
title_short | Multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
title_sort | multisystem inflammatory syndrome in an adult with severe hypoxaemia and thyroiditis responsive to corticosteroid and interleukin 6 inhibitor treatment |
topic | Case Reports: Unusual presentation of more common disease/injury |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092143/ https://www.ncbi.nlm.nih.gov/pubmed/35537767 http://dx.doi.org/10.1136/bcr-2021-248520 |
work_keys_str_mv | AT rojnukoolwanichthitirat multisysteminflammatorysyndromeinanadultwithseverehypoxaemiaandthyroiditisresponsivetocorticosteroidandinterleukin6inhibitortreatment AT kuagoolwongsechankanok multisysteminflammatorysyndromeinanadultwithseverehypoxaemiaandthyroiditisresponsivetocorticosteroidandinterleukin6inhibitortreatment AT vibhagoolasda multisysteminflammatorysyndromeinanadultwithseverehypoxaemiaandthyroiditisresponsivetocorticosteroidandinterleukin6inhibitortreatment AT pongpirulkrit multisysteminflammatorysyndromeinanadultwithseverehypoxaemiaandthyroiditisresponsivetocorticosteroidandinterleukin6inhibitortreatment |