Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer’s Disease Compared to Males

Multiple biological factors, including age, sex, and genetics, influence Alzheimer’s disease (AD) risk. Of the 6.2 million Americans living with Alzheimer’s dementia in 2021, 3.8 million are women and 2.4 million are men. The strongest genetic risk factor for sporadic AD is apolipoprotein E-e4 (APOE...

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Detalles Bibliográficos
Autores principales: Sandau, Ursula S., McFarland, Trevor J., Smith, Sierra J., Galasko, Douglas R., Quinn, Joseph F., Saugstad, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092217/
https://www.ncbi.nlm.nih.gov/pubmed/35573689
http://dx.doi.org/10.3389/fcell.2022.864022

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