MET Inhibition Sensitizes Rhabdomyosarcoma Cells to NOTCH Signaling Suppression

Rhabdomyosarcoma (RMS) is a pediatric myogenic soft tissue sarcoma. The Fusion-Positive (FP) subtype expresses the chimeric protein PAX3-FOXO1 (P3F) while the Fusion-Negative (FN) is devoid of any gene translocation. FP-RMS and metastatic FN-RMS are often unresponsive to conventional therapy. Theref...

Descripción completa

Detalles Bibliográficos
Autores principales: Perrone, Clara, Pomella, Silvia, Cassandri, Matteo, Pezzella, Michele, Milano, Giuseppe Maria, Colletti, Marta, Cossetti, Cristina, Pericoli, Giulia, Di Giannatale, Angela, de Billy, Emmanuel, Vinci, Maria, Petrini, Stefania, Marampon, Francesco, Quintarelli, Concetta, Taulli, Riccardo, Roma, Josep, Gallego, Soledad, Camero, Simona, Mariottini, Paolo, Cervelli, Manuela, Maestro, Roberta, Miele, Lucio, De Angelis, Biagio, Locatelli, Franco, Rota, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092259/
https://www.ncbi.nlm.nih.gov/pubmed/35574376
http://dx.doi.org/10.3389/fonc.2022.835642

Ejemplares similares

Ejemplares similares