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A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice
Conventional influenza vaccines fail to confer broad protection against diverse influenza A viruses with pandemic potential. Efforts to develop a universal influenza virus vaccine include refocusing immunity towards the highly conserved stalk domain of the influenza virus surface glycoprotein, hemag...
Autores principales: | Bliss, Carly M., Freyn, Alec W., Caniels, Tom G., Leyva-Grado, Victor H., Nachbagauer, Raffael, Sun, Weina, Tan, Gene S., Gillespie, Virginia L., McMahon, Meagan, Krammer, Florian, Hill, Adrian V.S., Palese, Peter, Coughlan, Lynda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092311/ https://www.ncbi.nlm.nih.gov/pubmed/34999208 http://dx.doi.org/10.1016/j.ymthe.2022.01.011 |
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