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A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV

BACKGROUND: The immunologic correlates of risk of Mycobacterium tuberculosis (Mtb) infection after BCG vaccination are unknown. The mechanism by which BCG influences the tuberculin skin test (TST) remains poorly understood. We evaluated CD4+ T-cell responses in infants exposed to HIV and uninfected...

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Detalles Bibliográficos
Autores principales:	Warr, Alex J., Anterasian, Christine, Shah, Javeed A, De Rosa, Stephen C., Nguyen, Felicia K., Maleche-Obimbo, Elizabeth, Cranmer, Lisa M., Matemo, Daniel, Mecha, Jerphason, Kinuthia, John, LaCourse, Sylvia M., John-Stewart, Grace C., Hawn, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092381/ https://www.ncbi.nlm.nih.gov/pubmed/35533496 http://dx.doi.org/10.1016/j.ebiom.2022.104023

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