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A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV
BACKGROUND: The immunologic correlates of risk of Mycobacterium tuberculosis (Mtb) infection after BCG vaccination are unknown. The mechanism by which BCG influences the tuberculin skin test (TST) remains poorly understood. We evaluated CD4+ T-cell responses in infants exposed to HIV and uninfected...
Autores principales: | Warr, Alex J., Anterasian, Christine, Shah, Javeed A, De Rosa, Stephen C., Nguyen, Felicia K., Maleche-Obimbo, Elizabeth, Cranmer, Lisa M., Matemo, Daniel, Mecha, Jerphason, Kinuthia, John, LaCourse, Sylvia M., John-Stewart, Grace C., Hawn, Thomas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092381/ https://www.ncbi.nlm.nih.gov/pubmed/35533496 http://dx.doi.org/10.1016/j.ebiom.2022.104023 |
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