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TP53 mutation defines a unique subgroup within complex karyotype de novo and therapy-related MDS/AML

A subset of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) show complex karyotype (CK), and these cases include a relatively high proportion of cases of therapy-related myeloid neoplasms and TP53 mutations. We aimed to evaluate the clinicopathologic features of outcome of 299 AML a...

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Detalles Bibliográficos
Autores principales: Weinberg, Olga K., Siddon, Alexa, Madanat, Yazan F., Gagan, Jeffrey, Arber, Daniel A., Dal Cin, Paola, Narayanan, Damodaran, Ouseph, Madhu M., Kurzer, Jason H., Hasserjian, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092405/
https://www.ncbi.nlm.nih.gov/pubmed/35073573
http://dx.doi.org/10.1182/bloodadvances.2021006239

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