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Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature

We present an unusual case of a 28-year-old female who had atypical trophoblastic proliferation on her endocervical curettage (ECC) performed at the time of a colposcopy. The indication for colposcopy was a Pap smear notable for atypical squamous cells of unknown significance, positive HPV. Initiall...

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Autores principales: Brodsky, Allison L., Hom-Tedla, Marianne, Fadare, Oluwole, McHale, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092518/
https://www.ncbi.nlm.nih.gov/pubmed/35574244
http://dx.doi.org/10.1016/j.gore.2022.100994
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author Brodsky, Allison L.
Hom-Tedla, Marianne
Fadare, Oluwole
McHale, Michael T.
author_facet Brodsky, Allison L.
Hom-Tedla, Marianne
Fadare, Oluwole
McHale, Michael T.
author_sort Brodsky, Allison L.
collection PubMed
description We present an unusual case of a 28-year-old female who had atypical trophoblastic proliferation on her endocervical curettage (ECC) performed at the time of a colposcopy. The indication for colposcopy was a Pap smear notable for atypical squamous cells of unknown significance, positive HPV. Initially conservative management was pursued, but given persistent atypia the patient ultimately decided to proceed with definitive management via hysterectomy. Final histologic assessment demonstrated an epithelioid trophoblastic tumor (ETT). This case highlights the unusual scenario of ETT presenting as atypical trophoblastic cells on endocervical curettage and the possible evolution of an atypical placental site nodule into an ETT.
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spelling pubmed-90925182022-05-12 Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature Brodsky, Allison L. Hom-Tedla, Marianne Fadare, Oluwole McHale, Michael T. Gynecol Oncol Rep Case Report We present an unusual case of a 28-year-old female who had atypical trophoblastic proliferation on her endocervical curettage (ECC) performed at the time of a colposcopy. The indication for colposcopy was a Pap smear notable for atypical squamous cells of unknown significance, positive HPV. Initially conservative management was pursued, but given persistent atypia the patient ultimately decided to proceed with definitive management via hysterectomy. Final histologic assessment demonstrated an epithelioid trophoblastic tumor (ETT). This case highlights the unusual scenario of ETT presenting as atypical trophoblastic cells on endocervical curettage and the possible evolution of an atypical placental site nodule into an ETT. Elsevier 2022-05-05 /pmc/articles/PMC9092518/ /pubmed/35574244 http://dx.doi.org/10.1016/j.gore.2022.100994 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Brodsky, Allison L.
Hom-Tedla, Marianne
Fadare, Oluwole
McHale, Michael T.
Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
title Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
title_full Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
title_fullStr Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
title_full_unstemmed Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
title_short Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
title_sort persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic tumor: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092518/
https://www.ncbi.nlm.nih.gov/pubmed/35574244
http://dx.doi.org/10.1016/j.gore.2022.100994
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