Insulin Therapy is Associated With Increased Myocardial Interstitial Fibrosis and Cardiomyocyte Apoptosis in a Rodent Model of Experimental Diabetes

The incidence of diabetes mellitus (DM) is rising. DM is a risk factor for developing left ventricular (LV) dysfunction and adverse cardiovascular outcomes. Insulin, commonly used to treat DM, is associated with further worsening of such outcomes. Yet, the pathophysiology of the adverse properties o...

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Detalles Bibliográficos
Autores principales: Adel, Fadi W., Zheng, Ye, Wan, Siu-Hin, Greason, Christie, Pan, Shuchong, Ameenuddin, Syed, Chen, Horng H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092527/
https://www.ncbi.nlm.nih.gov/pubmed/35574440
http://dx.doi.org/10.3389/fphys.2022.890907

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