Cargando…

Upregulation of PKN1 as a Prognosis Biomarker for Endometrial Cancer

BACKGROUND: Several markers of survival among endometrial cancer (EC) patients have been proposed, namely, the oncoprotein stathmin, RAF kinase inhibitor (RKIP), Cyclin A, GATA-binding protein 3 (GATA3), and growth and differentiation factor-15 (GDF-15). Their elevated expression correlated signific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Govorov, Igor, Attarha, Sanaz, Kovalevska, Larysa, Andersson, Emil, Kashuba, Elena, Mints, Miriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092572/ https://www.ncbi.nlm.nih.gov/pubmed/35533253 http://dx.doi.org/10.1177/10732748221094797

Ejemplares similares

STK4 protein expression pattern follows different trends in endometrioid and serous endometrial adenocarcinoma upon tumor progression
por: Govorov, Igor, et al.
Publicado: (2022)

PKN1 modulates TGFβ and EGF signaling in HEC-1-A endometrial cancer cell line
por: Attarha, Sanaz, et al.
Publicado: (2014)

Mitochondrial ribosomal protein S18-2 is highly expressed in endometrial cancers along with free E2F1
por: Mints, Miriam, et al.
Publicado: (2016)

Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers
por: Attarha, S, et al.
Publicado: (2013)

The Prognostic Role of LRIG Proteins in Endometrial Cancer
por: Razumova, Zoia, et al.
Publicado: (2021)

A Comparative Study on the Viability of Normal and Cancerous Cells upon Irradiation with a Steady Beam of THz Rays
por: Kovalevska, Larysa, et al.
Publicado: (2022)

Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer
por: Liu, Liya, et al.
Publicado: (2021)

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2
por: Mushtaq, Muhammad, et al.
Publicado: (2020)

The role of PKN1 in glioma pathogenesis and the antiglioma effect of raloxifene targeting PKN1
por: Hao, Yubing, et al.
Publicado: (2023)

Evaluation of dyskerin expression and the Cajal body protein WRAP53β as potential prognostic markers for patients with primary vaginal carcinoma
por: Ranhem, Cecilia, et al.
Publicado: (2022)

Phosphorylation of Mycobacterium tuberculosis Ser/Thr Phosphatase by PknA and PknB
por: Sajid, Andaleeb, et al.
Publicado: (2011)

Genetic and biochemical analysis of the serine/threonine protein kinases PknA, PknB, PknG and PknL of Corynebacterium glutamicum: evidence for non-essentiality and for phosphorylation of OdhI and FtsZ by multiple kinases
por: Schultz, Christian, et al.
Publicado: (2009)

PKC and PKN in heart disease
por: Marrocco, Valeria, et al.
Publicado: (2019)

Postpartum Hemorrhage in Women with Von Willebrand Disease – A Retrospective Observational Study
por: Govorov, Igor, et al.
Publicado: (2016)

Correction: Postpartum Hemorrhage in Women with Von Willebrand Disease - A Retrospective Observational Study
por: Govorov, Igor, et al.
Publicado: (2017)

Protein Kinase C-Related Kinase (PKN/PRK). Potential Key-Role for PKN1 in Protection of Hypoxic Neurons
por: Thauerer, Bettina, et al.
Publicado: (2014)

Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts
por: Darekar, Suhas D., et al.
Publicado: (2015)

Blood inflammatory and endothelial markers in women with von Willebrand disease
por: Govorov, Igor, et al.
Publicado: (2019)

Prokineticin 1 is up‐regulated by insulin in decidualizing human endometrial stromal cells
por: Ujvari, Dorina, et al.
Publicado: (2017)

Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility
por: Zeng, Jumei, et al.
Publicado: (2020)

Thrombin generation during a regular menstrual cycle in women with von Willebrand disease
por: Govorov, Igor, et al.
Publicado: (2018)

The Extracytoplasmic Domain of the Mycobacterium tuberculosis Ser/Thr Kinase PknB Binds Specific Muropeptides and Is Required for PknB Localization
por: Mir, Mushtaq, et al.
Publicado: (2011)

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion
por: Quétier, Ivan, et al.
Publicado: (2016)

Upregulated ENC1 predicts unfavorable prognosis and correlates with immune infiltration in endometrial cancer
por: He, Lingling, et al.
Publicado: (2022)

Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN1
por: Mashud, Rana, et al.
Publicado: (2017)

Fragmentation of Protein Kinase N (PKN) in the Hydrocephalic Rat Brain
por: Okii, Norifumi, et al.
Publicado: (2007)

PKN3 is the major regulator of angiogenesis and tumor metastasis in mice
por: Mukai, Hideyuki, et al.
Publicado: (2016)

Antimycobacterial and PknB Inhibitory Activities of Venezuelan Medicinal Plants
por: Aranaga, C. A., et al.
Publicado: (2020)

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells
por: Jilg, Cordula A., et al.
Publicado: (2014)

PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels
por: Safari, Motahareh Solina, et al.
Publicado: (2021)

PKN1 Kinase: A Key Player in Adipocyte Differentiation and Glucose Metabolism
por: Herrerías-González, Fernando, et al.
Publicado: (2023)

Metabolomic Biomarkers for Detection, Prognosis and Identifying Recurrence in Endometrial Cancer
por: Njoku, Kelechi, et al.
Publicado: (2020)

Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer
por: Scott, Fiona, et al.
Publicado: (2020)

Structural Analysis of Staphylococcus aureus Serine/Threonine Kinase PknB
por: Rakette, Sonja, et al.
Publicado: (2012)

Staphylococcal PknB as the First Prokaryotic Representative of the Proline-Directed Kinases
por: Miller, Malgorzata, et al.
Publicado: (2010)

Enhanced ranking of PknB Inhibitors using data fusion methods
por: Seal, Abhik, et al.
Publicado: (2013)

PKN2 and Cdo interact to activate AKT and promote myoblast differentiation
por: Lee, Sang-Jin, et al.
Publicado: (2016)

The interaction of p130Cas with PKN3 promotes malignant growth
por: Gemperle, Jakub, et al.
Publicado: (2018)

Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents
por: Lougheed, Kathryn E.A., et al.
Publicado: (2011)

Regulatory Domain Selectivity in the Cell-Type Specific PKN-Dependence of Cell Migration
por: Lachmann, Sylvie, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_r1qv5ca6e2vdpmlhslmudqrb8q