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Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic

The Dominican Republic (DR) has the second-highest prevalence of HIV infection in the Caribbean, but viral suppression and treatment adherence are not well understood. We conducted a cross-sectional study among people living with HIV/AIDS(PLWHA) to fill in the knowledge gap. Questionnaire was used t...

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Autores principales: McCarthy, Meghan, Tao, Jun, Lerebours, Alain, Rodriguez, Claudia, Flanigan, Timothy P, Sanchez, Martha C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092578/
https://www.ncbi.nlm.nih.gov/pubmed/35532067
http://dx.doi.org/10.1177/23259582221096522
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author McCarthy, Meghan
Tao, Jun
Lerebours, Alain
Rodriguez, Claudia
Flanigan, Timothy P
Sanchez, Martha C
author_facet McCarthy, Meghan
Tao, Jun
Lerebours, Alain
Rodriguez, Claudia
Flanigan, Timothy P
Sanchez, Martha C
author_sort McCarthy, Meghan
collection PubMed
description The Dominican Republic (DR) has the second-highest prevalence of HIV infection in the Caribbean, but viral suppression and treatment adherence are not well understood. We conducted a cross-sectional study among people living with HIV/AIDS(PLWHA) to fill in the knowledge gap. Questionnaire was used to collect demographic data, antiretroviral therapy (ART) adherence, and barriers and facilitators to HIV care. Viral load and other clinical information were extracted through chart reviews. Descriptive analyzes and logistic regression were conducted to explore factors associated with non-viral suppression and imperfect ART adherence. Of 193 PLWHA 83.9% were virally suppressed. Those that were non-virally suppressed were more likely of being male (odds ratio [OR]: 2.55, 95% confidence interval [CI]: 1.17-5.58) and less likely of being unemployed (OR: 0.28, 95% CI: 0.08-0.96). However, being male (OR: 0.78, 95% CI:0.40-1.53) and unemployed (OR: 0.28, 95% CI:0. 08-1.21) were less likely to report imperfect adherence. Tailored interventions are needed to improve adherence and viral suppression in DR.
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spelling pubmed-90925782022-05-12 Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic McCarthy, Meghan Tao, Jun Lerebours, Alain Rodriguez, Claudia Flanigan, Timothy P Sanchez, Martha C J Int Assoc Provid AIDS Care Original Research Article The Dominican Republic (DR) has the second-highest prevalence of HIV infection in the Caribbean, but viral suppression and treatment adherence are not well understood. We conducted a cross-sectional study among people living with HIV/AIDS(PLWHA) to fill in the knowledge gap. Questionnaire was used to collect demographic data, antiretroviral therapy (ART) adherence, and barriers and facilitators to HIV care. Viral load and other clinical information were extracted through chart reviews. Descriptive analyzes and logistic regression were conducted to explore factors associated with non-viral suppression and imperfect ART adherence. Of 193 PLWHA 83.9% were virally suppressed. Those that were non-virally suppressed were more likely of being male (odds ratio [OR]: 2.55, 95% confidence interval [CI]: 1.17-5.58) and less likely of being unemployed (OR: 0.28, 95% CI: 0.08-0.96). However, being male (OR: 0.78, 95% CI:0.40-1.53) and unemployed (OR: 0.28, 95% CI:0. 08-1.21) were less likely to report imperfect adherence. Tailored interventions are needed to improve adherence and viral suppression in DR. SAGE Publications 2022-05-09 /pmc/articles/PMC9092578/ /pubmed/35532067 http://dx.doi.org/10.1177/23259582221096522 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
McCarthy, Meghan
Tao, Jun
Lerebours, Alain
Rodriguez, Claudia
Flanigan, Timothy P
Sanchez, Martha C
Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic
title Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic
title_full Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic
title_fullStr Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic
title_full_unstemmed Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic
title_short Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic
title_sort evaluating barriers to viral suppression among people with hiv in santiago, dominican republic
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092578/
https://www.ncbi.nlm.nih.gov/pubmed/35532067
http://dx.doi.org/10.1177/23259582221096522
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