Nickel(ii)-catalyzed tandem C(sp(2))–H bond activation and annulation of arenes with gem-dibromoalkenes

A nickel(ii)/silver(i)-catalyzed tandem C(sp(2))–H activation and intramolecular annulation of arenes with dibromoalkenes has been successfully achieved, which offers an efficient approach to the 3-methyleneisoindolin-1-one scaffold. Attractive features of this system include its low cost, ease of o...

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Detalles Bibliográficos
Autores principales: Shi, Yun, Li, Meng-Sheng, Zhang, Fangdong, Chen, Baohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092601/
https://www.ncbi.nlm.nih.gov/pubmed/35558433
http://dx.doi.org/10.1039/c8ra03278e
Descripción
Sumario:A nickel(ii)/silver(i)-catalyzed tandem C(sp(2))–H activation and intramolecular annulation of arenes with dibromoalkenes has been successfully achieved, which offers an efficient approach to the 3-methyleneisoindolin-1-one scaffold. Attractive features of this system include its low cost, ease of operation, and its ability to access a wide range of isoindolinones.

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