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Mitochondrial 1555 G>A variant as a potential risk factor for childhood glioblastoma

BACKGROUND: Childhood glioblastoma multiforme (GBM) is a highly aggressive disease with low survival, and its etiology, especially concerning germline genetic risk, is poorly understood. Mitochondria play a key role in putative tumorigenic processes relating to cellular oxidative metabolism, and mit...

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Detalles Bibliográficos
Autores principales: Li, Shaobo, Gai, Xiaowu, Myint, Swe Swe, Arroyo, Katti, Morimoto, Libby, Metayer, Catherine, de Smith, Adam J, Walsh, Kyle M, Wiemels, Joseph L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092641/
https://www.ncbi.nlm.nih.gov/pubmed/35571988
http://dx.doi.org/10.1093/noajnl/vdac045