Inhibition of NOS1 promotes the interferon response of melanoma cells

BACKGROUND: NOS1 expression predicts poor prognosis in patients with melanoma. However, the molecular function of NOS1 in the type I IFN response and immune escape of melanoma is still unknown. METHODS: The CRISPR/Cas9 system was used to generate NOS1-knockout melanoma cells and the biological chara...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Zou, Zhiwei, Wang, Qianli, Gao, Wenwen, Zeng, Sisi, Ye, Shuangyan, Xu, Pengfei, Huang, Mengqiu, Li, Keyi, Chen, Jianping, Zhong, Zhuo, Zhang, Qianbing, Hao, Bingtao, Liu, Qiuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092760/
https://www.ncbi.nlm.nih.gov/pubmed/35538490
http://dx.doi.org/10.1186/s12967-022-03403-w

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