Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma

BACKGROUND: Lung cancer is the leading cause of cancer death, partially owing to its extensive heterogeneity. The analysis of intertumor heterogeneity has been limited by an inability to concurrently obtain tissue from synchronous metastases unaltered by multiple prior lines of therapy. METHODS: In...

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Detalles Bibliográficos
Autores principales: Chen, Runzhe, Li, Jun, Fujimoto, Junya, Hong, Lingzhi, Hu, Xin, Quek, Kelly, Tang, Ming, Mitra, Akash, Behrens, Carmen, Chow, Chi-Wan, Jiang, Peixin, Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Tan, Dongfeng, Heymach, John V., Wistuba, Ignacio, Futreal, P. Andrew, Gibbons, Don L., Byers, Lauren A., Zhang, Jianjun, Reuben, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092788/
https://www.ncbi.nlm.nih.gov/pubmed/35546239
http://dx.doi.org/10.1186/s13046-022-02361-x

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